“Now the Monroe County Mosquito Control District has given the final permission needed. What could possibly go wrong? We don’t know, because EPA unlawfully refused to seriously analyze environmental risks, now without further review of the risks, the experiment can proceed,” she added.
Approved by the Environment Protection Agency in May, the pilot project is designed to test if a genetically modified mosquito is a viable alternative to spraying insecticides to control the Aedes aegypti. It’s a species of mosquito that carries several deadly diseases, such as Zika, dengue, chikungunya and yellow fever.
The mosquito, named OX5034, has been altered to produce female offspring that die in the larval stage, well before hatching and growing large enough to bite and spread disease. Only the female mosquito bites for blood, which she needs to mature her eggs. Males feed only on nectar, and are thus not a carrier for disease.
A long fight in Florida
In June the state of Florida issued an Experimental Use Permit after seven state agencies unanimously approved the project. But it’s taken over a decade to obtain that approval.
In 2009 and 2010, local outbreaks of dengue fever, which is spread by the Aedes aegypti, left the Florida Keys Mosquito Control District desperate for new options. Despite an avalanche of effort — from aerial, truck and backpack spraying to the use of mosquito-eating fish — local control efforts to contain the Aedes aegypti with larvicide and pesticide had been largely ineffective.
And costly, too. Even though Aedes aegypti is only 1% of its mosquito population, Florida Keys Mosquito Control typically budgets more than $1 million a year, a full tenth of its total funding, to fighting it.
In 2012, the district reached out to Oxitec for help. The company had developed a male mosquito named OX513A, programmed to die before adulthood unless it was grown in water that contained the antibiotic tetracycline.
Batches of the sterile OX513A would be allowed to live and mate with females; however, their male and female offspring would inherit the “kill” programming and die, thus limiting population growth.
Public relations campaigns reminding Floridians that the GMO mosquito doesn’t bite because he’s male didn’t completely solve the problem. Media reports quoted angry residents refusing to be treated as “guinea pigs” for the “superbug” or “Robo-Frankenstein” mosquito.
The EPA spent years investigating the mosquito’s impact on both human health and the environment, allowing time for public input. But in the midst of the evaluation, Oxitec developed a second-generation “Friendly Mosquito” technology and withdrew the application for the first.
The new male mosquito, OX5034, is programmed to kill only female mosquitoes, with males surviving for multiple generations and passing along the modified genes to subsequent male offspring.
The EPA permit requires Oxitec to notify state officials 72 hours before releasing the mosquitoes and conduct ongoing tests for at least 10 weeks to ensure none of the female mosquitoes reach adulthood.
However, environmental groups worry that the spread of the genetically modified male genes into the wild population could potentially harm threatened and endangered species of birds, insects and mammals that feed on the mosquitoes.
“The release of genetically engineered mosquitoes will needlessly put Floridians, the environment and endangered species at risk in the midst of a pandemic,” said Dana Perls, food and technology program manager at Friends of the Earth, in Wednesday’s statement.